Grant-in-Aid for Transformative Research Areas (A) 2024-2029
The 4th Area Seminar was held as a lecture by Prof. Gemma Marfany of the University of Barcelona.
Professor Marfany’s specialty is genetics, and she gave a presentation entitled “Using 2D and 3D retinal organoids with CRISPR-Cas9 gene editing hiPSCs to model retinal diseases”.
In addition to the results of her research using knockout mice, she also introduced her recent research on modeling diseases using human iPS cell-derived neurons and retinal organoids. The microscope photo of the organoid with the outer segment of photoreceptor cells growing like a brush was a highlight. She also told us about recent trends in new drug development, explaining that in some countries, animal testing can be omitted if appropriate experiments are carried out using organoids derived from human cells. The presentation was easy to understand even for members and students outside the field, and there were many questions during the Q&A session.